Amarin 45.5mg/2ml Injection is a competitive H1 histamine receptor antagonist. Like other alkylamine antihistamines, it also antagonizes muscarinic cholinergic receptors and has local anesthetic properties, although these effects are not achieved at therapeutic doses.
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Pheniramine is used for treating allergic conditions like urticaria or hay fever. It is also used as an over-the-counter sleeping pill similar to other sedating antihistamines. The active constituent of this medication is an alkylamine derivative, a histamine H1-receptor antagonist with anticholinergic and moderate sedative effects. Besides all of its uses, it is also found in eyedrops used to treat allergic conjunctivitis.
Avoid consumption of alcohol while receiving Amarin 45.5mg/2ml Injection as it may increase the adverse central nervous system effects of this medicine.
Amarin 45.5mg/2ml Injection should be used with caution in pregnant women only if advised by the doctor. Consult your doctor before receiving it.
Amarin 45.5mg/2ml Injection should be used with caution in breast-feeding women only if advised by the doctor. Consult your doctor before receiving it.
Do not drive or use machines if you feel drowsy after receiving Amarin 45.5mg/2ml Injection.
There is limited information available on the use of Amarin 45.5mg/2ml Injection in patients with kidney disease. Please consult your doctor.
Amarin 45.5mg/2ml Injection should be used with caution in patients having severe hepatic disease and your doctor may adjust the dose in such patients. Consult your doctor before receiving it.
Motion or travel sickness occurs when a person feels sick while traveling, typically due to the repetitive motion of a vehicle or any movement that disrupts the inner ear. The disturbance in the inner ear leads to symptoms such as nausea, vomiting, and dizziness.
An allergy is a condition where the immune system reacts abnormally to foreign substances such as pollen, dust mites, mold spores, food, pet dander, insect stings, and certain medications. Common types of allergies include drug allergy, food allergy, contact dermatitis, latex allergy, allergic asthma, seasonal allergies, animal allergies, and anaphylaxis (a severe allergic reaction). Symptoms can vary from mild, like rashes, hives, itching, watery eyes, and a runny nose, to severe reactions that can be life-threatening.
Meniere's disease is a disorder of the inner ear that causes episodes of vertigo (a spinning sensation), which can result in severe nausea and loss of balance. Other symptoms include hearing loss, tinnitus (a ringing sound in the ear), and a feeling of pressure or fullness in the ear.
Pheniramine, the active ingredient in Avil, competes with histamine for the H1 receptor, acting as an inverse agonist. This reduces itching, vasodilation, and capillary leakage, leading to less redness and edema. In the CNS, inverse agonism of the H1 receptor is responsible for sedation, a common effect of first-generation antihistamines like pheniramine.
Injection Solution: For adults and young people aged 12 years or over, 1.0-2.0 ml IV/IM once or twice daily. For children, the dosage varies based on age and body weight.
Amarin 45.5mg/2ml Injection will be administered to you only by a doctor or a nurse into a vein as a slow intravenous injection or into a muscle (intramuscularly). To infants and children up to 12 years of age, Amarin 45.5mg/2ml Injection will be given intramuscularly. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and general health condition.
Pregnancy Category A: Use only if strictly indicated.
Store in a cool, dry place protected from light. Keep out of reach of children. Use only as prescribed by a physician.
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